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However, overexpression of serpina3n showed that antagonizing selective pathogenic proteases in the muscles of dystrophic mice is protective.
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However, overexpression of serpina3n showed that antagonizing selective pathogenic proteases in the muscles of dystrophic mice is protective.
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Apart from the z allele, other common variants of serpina1 are described and include the m1, m2, and m3 alleles, linked to normal circulating protein levels; and the s allele, which results from the amino acid replacement e264v at the shutter region of the molecule 1 , 9 .
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