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/i Okategoriserade/av fmnmRelationship between the auc of indinavir and the virological response after 6 months of treatment.
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/i Okategoriserade/av fmnmIndinavir is not recommended in children below 18 years of age.
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/i Okategoriserade/av fmnmIndinavir is a strong cyp3a inhibitor; eliglustat is a cyp3a and cyp2d6 substrate.
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/i Okategoriserade/av fmnmOther side effects reported since indinavir has been marketed include allergic reactions; severe skin reactions; yellowing of the skin and or eyes; heart problems including heart attack; stroke; abdominal swelling; indigestion; inflammation of the kidneys; decreased kidney function; inflammation of the pancreas; joint pain; depression; itching; hives; change in skin color; hair loss; ingrown toenails with or without infection; crystals in the urine; painful urination; numbness of the mouth; increased cholesterol; pain and difficulty moving shoulder.
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/i Okategoriserade/av fmnm75 kg ; the usual adult dose of indinavir is 800 mg q8h, which is equal to 33 mg kg of mw 800 mg 24 kg of mw q8h.
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/i Okategoriserade/av fmnmEthotoin major hydantoins like phenytoin, ethotoin, fosphenytoin may increase the metabolism of indinavir and lead to decreased efficacy.
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