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Because orlistat may decrease the absorption of fat-soluble vitamins, a standard multiple-vitamin supplement is recommended daily during therapy to prevent abnormalities in vitamin serum concentrations.
Information about Orlistat.
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Orlistat blocks your body’s absorption of some fat-soluble vitamins and beta caroteneThereforewhen you use orlistat you should take a daily multivitamin that contains vitamins ADEKand beta-caroteneRead the label to find a multivitamin product that contains these vitaminsTake the multivitamin once a day2 hours before or 2 hours after taking orlistator take the multivitamin at bedtimeAsk your doctor or pharmacist any questions you might have about taking a multivitamin while you are taking orlistat.
Stop using orlistat and call your doctor at once if you have a serious side effect such as:
Orlistat is a reversible inhibitor of gastrointestinal lipasesIt exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine residue site of gastric and pancreatic lipasesThe inactivated enzymes are thus unavailable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglyceridesAs undigested triglycerides are not absorbedthe resulting caloric deficit may have a positive effect on weight control.
It is important for you to keep a written list of all of the prescription and nonprescriptionover-the-countermedicines you are takingas well as any products such as vitaminsmineralsor other dietary supplementsYou should bring this list with you each time you visit a doctor or if you are admitted to a hospitalIt is also important information to carry with you in case of emergencies.
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a review of several thousand adverse event reports from the food and drug administration associated with orlistat the active ingredient in the over-the-counter otc weight-loss drug alli and the prescription drug xenical–has further strengthened our earlier advice skip this drug.