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The mutagenic potential of cabergoline was evaluated and found to be negative in a battery of in vitro testsThese tests included the bacterial mutationAmestest with Salmonella typhimuriumthe gene mutation assay with Schizosaccharomyces pombe P1 and V79 Chinese hamster cellsDNA damage and repair in Saccharomyces cerevisiae D4and chromosomal aberrations in human lymphocytesCabergoline was also negative in the bone marrow micronucleus test in the mouse.
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