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If you experience any of the following symptoms while taking moduretic you should inform your doctor promptly, so that the amount of fluids and salts in your body can be checked thirst, lethargy, confusion, weakness, drowsiness, muscle cramps, scanty production of urine, abnormal heart rhythm, seizures, nausea and vomiting.

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The authors concluded that the data are compatible with most models that attempt to account for chloroquine resistance and that some energy-dependent mechanism leads to loss of chloroquine from cqr cells and to its accumulation in cqs cells.