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Th inhibitoy activity aciclovi is highly slctiv du tits ainity th nzym thymidin kinas (TK) ncodd by HSV and VZV. This vial nzym convts aciclovi intaciclovi monophosphat, a nuclotid analogu. Th monophosphat is uth convtd intdiphosphat by cllula guanylat kinas and inttiphosphat by a finasteride china buy. numb cllula nzyms. In vit, aciclovi tiphosphat stops plication th hps vial DNA. This is accomplishd in th ways: 1) comptitiv inhibition vial DNA polymas; 2) incopoation intand tmination th gowing vial DNA chain; and 3) inactivation th vial DNA polymas. Th gat antivial activity aciclovi against HSV compad with VZV is du tits micint phosphoylation by th vial TK.
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Th bith dcts dscibd amongst subjcts xposd taciclovi hav not shown any uniqunss consistnt pattn tsuggst a common caus. Th us aciclovi cam should b considd only whn th potntial bnits outwigh th possibility unknown isks.
ACIVI Cam is indicatd th tatmnt cunt hps labialis (cold sos) in adults and adolscnts (12 yas ag and old).
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